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    where can i buy priligy online safely Selection of endpoint is important while for the change arm, longer PFS might be expected, OS has multiple plausible outcomes H0 no change in OS, due to the same clocklike rate of resistance development; H1 longer OS, due to the change arm have a higher chance of durable response with earlier therapy switch; H2 shorter OS, due to premature discontinuation of current therapy before attaining maximum benefit

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